NAD+ (Hello Energy): What It Is & Common Questions
This article is for general informational purposes only and is not medical advice.
Please consult your primary care physician or your doctor through the Member Portal before making any decisions about your treatment. This content is intended as a general guide only.
What Is NAD+ (Hello Energy)?
Hello Energy is a physician-prescribed NAD+ therapy. NAD+ (nicotinamide adenine dinucleotide) is a coenzyme your cells use to make energy. It powers your mitochondria, activates sirtuins (often called "longevity genes"), and crosses into the brain to support mental clarity. It's compounded, personalized to your prescription, and shipped overnight cold-packed from a 503A licensed pharmacy.
Two Ways to Take It
| Format | How you take it | Absorption |
|---|---|---|
| Injection | Daily subcutaneous (Mon–Fri), 31G insulin syringe | ~95% |
| Nasal spray | Daily intranasal spray — no needles | ~50% |
Choose the injection for the highest absorption, or the nasal spray if you'd rather not inject. Both contain the same active ingredient.
What It May Help With
- Restored afternoon energy
- Mental clarity that lasts through the evening
- Faster workout recovery
- Sleep that actually resets you
NAD+ doesn't deplete with use, and its effects tend to compound over months.
Who It's For
- Hard workers running on empty
- Perimenopausal women
- Active people whose recovery has slowed
- Burnt-out parents
- Adults 25+
Who It's NOT For
- Anyone pregnant or breastfeeding
- People with an active cancer diagnosis (without oncologist approval)
- Anyone under 25 years old
- People looking for a stimulant
- Anyone who hasn't seen a doctor in 5+ years
- People unwilling to self-inject — though the nasal spray is a needle-free option
Side Effects
Most common: mild flushing or warmth at the injection site, lasting a few minutes. Less common: brief nausea, headache, or some fatigue on the day of injection. Tell your clinician about anything that concerns you.
What to Expect Over Time
- Week 1: A subtle shift in energy
- Weeks 2–3: Mental fog starts to lift; clearer focus
- Month 2: Workout recovery improves
- Month 3: The compounding effect becomes obvious
- Months 6–12: A return to a remembered baseline of energy
Frequently Asked Questions
Injection or nasal spray — which should I pick? The injection absorbs better (~95% vs. ~50%), so it's the stronger option. The nasal spray is for members who'd prefer to skip needles entirely. Both use the same active ingredient.
Does the injection hurt? It uses a 31G insulin syringe — the same size diabetics use multiple times a day — so it's a minor pinch for most people.
How quickly will I feel it? The earliest shifts in energy and sharpness usually show up around weeks 2–3, with deeper changes compounding over months 2–6.
Do I need a prescription? Yes. NAD+ therapy is prescription-only. A U.S.-licensed clinician reviews your intake first, and you pay nothing if you're not approved.
Is it FDA-approved? Compounded medications are not FDA-approved. Your NAD+ contains the same active ingredient used in research settings and is prepared by a 503A licensed pharmacy for you.
How is it shipped and stored? It ships overnight, cold-packed. Refrigerate it on arrival and follow the storage instructions on your vial label.
Questions?
For ordering or account help, contact support at support@coreagerx.com or (307) 405-1638. For medical questions, message your clinician through the member portal.
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